Xyanide is a sci-fi shooter inspired by classic arcade games such as Gradius and R-Type. Rather than adopt a side-scrolling perspective, however, the game employs a combination of 3D graphics and 2D movement, allowing for a more cinematic feel. The object is to defeat a sinister witch named Aguira, who has conjured an army of evil from the dark recesses of her mind. Players must battle through six deadly environments filled with more than 100 waves of enemy vessels and creatures.
While the game follows the familiar shooter template of acquiring power-ups and engaging in both mid- and end-level boss fights, Xyanide offers a new twist with its mutation element. As players advance through hostile space, their ship's firing rate, damage capabilities, and power-up effects can mutate into faster or stronger versions. Other notable design choices include dual analog support for maneuvering and firing weapons, five difficulty options, and branching levels with multiple paths to victory. ~ Scott Alan Marriott, All Game Guide